Solution

In this puzzle, the results of the calculations are the atomic numbers of chemical elements. Replacing them with the element symbols provides the solution.

Equation provided	Result		Symbol
Flags flags − Signals signals + Calendar holidays	36 − 27 + 18	27	Co
Tap Code words × Logical Buttons round buttons − Simon Sends words	100 × 3 − 293	7	N
Crazy Talk phrases × Sonic & Knuckles zones − Pie digits in manual	85 × 6 − 500	10	Ne
Cheap Checkout items + Web Design websites − Pattern Cube cubes	46 + 8 − 48	6	C
Zoo animals + Timezone timezones − Double-Oh cells	79 + 24 − 81	22	Ti
Bitmaps pixels + Colorful Madness buttons − Word Search words	64 + 20 − 76	8	O
Mafia names + Lasers hatches − Extended Password passwords	50 + 9 − 52	7	N
Monsplode, Fight! moves + Splitting the Loot bags − Functions functions	41 + 7 − 42	6	C
Dragon Energy words + Simon Samples samples − Dominoes dominoes	30 + 4 − 32	2	He
Hexamaze cells on module + Simon Speaks speech bubbles − Maritime Flags flags	37 + 9 − 40	6	C
Mashematics maximum + Friendship elements of harmony − The Swan seconds	99 + 28 − 108	19	K

CONNECTION CHECK